“Hiccup” in HD Gene Contributes to Age of HD Onset

Dr. Leora Fox from Huntington’s Disease Society of America keeps you up-to-date on HDSA research activities, recently published work about Huntington’s disease, historical moments in HD research and more. This week, she discusses a new finding: a vast majority of people with HD have a certain type of genetic “hiccup” near the end of their CAG repeat – one CAA.  Very rarely, this CAA hiccup occurs twice (for about 1 in 100 people with HD). In these individuals, symptoms tend to occur later in life. Even more rarely, the CAA hiccup is absent (for about 1 in 300 people with HD). For these individuals, symptoms tend to occur earlier. This discovery was made simultaneously by two separate research groups working with data from more than 9,000 individuals with HD, and formally published this month.

Read more on her blog.

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The Editorial Team at Lake Oconee Health is made up of skilled health and wellness writers and experts, led by Daniel Casciato who has over 25 years of experience in healthcare writing. Since 1998, we have produced compelling and informative content for numerous publications, establishing ourselves as a trusted resource for health and wellness information. We aim to provide our readers with valuable insights and guidance to help them lead healthier and happier lives.